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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC6
All Species:
19.39
Human Site:
S403
Identified Species:
32.82
UniProt:
Q99741
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99741
NP_001245.1
560
62720
S403
R
A
I
E
I
V
E
S
D
V
K
S
Q
T
I
Chimpanzee
Pan troglodytes
XP_001170406
560
62717
S403
R
A
I
E
I
V
E
S
D
V
K
S
Q
T
I
Rhesus Macaque
Macaca mulatta
XP_001096756
559
62520
E402
R
R
A
I
E
I
V
E
S
D
V
K
S
Q
T
Dog
Lupus familis
XP_537648
559
62507
S402
R
A
I
E
I
V
E
S
D
V
K
S
Q
T
V
Cat
Felis silvestris
Mouse
Mus musculus
O89033
562
62595
S405
R
A
I
E
I
V
E
S
D
V
R
S
Q
T
V
Rat
Rattus norvegicus
NP_001101768
561
62295
S404
R
A
I
E
I
V
E
S
D
V
R
S
Q
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519126
361
39672
G219
A
R
E
L
F
Q
E
G
A
S
K
P
A
G
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081844
554
60731
R398
E
I
V
E
A
D
V
R
G
Q
T
V
L
K
P
Zebra Danio
Brachydanio rerio
NP_001120805
561
61262
R404
R
K
A
L
D
I
C
R
R
A
V
E
I
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648247
662
75116
K502
Q
Q
K
R
D
G
E
K
E
F
N
M
K
A
L
Honey Bee
Apis mellifera
XP_625142
549
62089
E391
R
R
V
I
E
L
T
E
S
H
K
L
A
Q
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999666
582
64455
K415
P
S
G
G
S
P
R
K
A
L
L
S
P
I
K
Poplar Tree
Populus trichocarpa
XP_002299817
498
55546
A356
S
A
I
E
I
L
E
A
E
L
R
E
S
T
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P09119
513
58018
T371
Q
V
P
L
T
P
T
T
S
P
V
K
K
S
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96
89.1
N.A.
79.5
80
N.A.
45.3
N.A.
63.7
49
N.A.
33.9
36
N.A.
40
Protein Similarity:
100
100
97.5
93.5
N.A.
87.3
88.9
N.A.
52.8
N.A.
77.5
67.3
N.A.
52.1
57.3
N.A.
58.5
P-Site Identity:
100
100
6.6
93.3
N.A.
86.6
86.6
N.A.
13.3
N.A.
6.6
6.6
N.A.
6.6
20
N.A.
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
13.3
N.A.
13.3
13.3
N.A.
33.3
33.3
N.A.
20
Percent
Protein Identity:
25.8
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
46.4
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
40
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
43
15
0
8
0
0
8
15
8
0
0
15
8
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
15
8
0
0
36
8
0
0
0
0
0
% D
% Glu:
8
0
8
50
15
0
58
15
15
0
0
15
0
0
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
8
0
8
8
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
43
15
43
15
0
0
0
0
0
0
8
8
22
% I
% Lys:
0
8
8
0
0
0
0
15
0
0
36
15
15
8
8
% K
% Leu:
0
0
0
22
0
15
0
0
0
15
8
8
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
8
0
8
0
0
15
0
0
0
8
0
8
8
0
8
% P
% Gln:
15
8
0
0
0
8
0
0
0
8
0
0
36
15
0
% Q
% Arg:
58
22
0
8
0
0
8
15
8
0
22
0
0
0
8
% R
% Ser:
8
8
0
0
8
0
0
36
22
8
0
43
15
8
8
% S
% Thr:
0
0
0
0
8
0
15
8
0
0
8
0
0
43
8
% T
% Val:
0
8
15
0
0
36
15
0
0
36
22
8
0
8
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _